Clinical Trial Committee

17 Jan

Written By 3B Digital

Chair: Juliet Gray (UK) Juliet.gray@uhs.nhs.uk
Vice chair: Giuseppe Barone (UK) giuseppe.barone@gosh.nhs.uk

The SIOPEN CTC was established in June 2020, with the aim of facilitating the opening and running SIOPEN clinical trials.

The objectives of the CTC include:

To create and maintain a database of all SIOPEN clinical trials
To regularly review the progress of all SIOPEN clinical trials, from concept through to data publication
To facilitate the timely opening of studies
To Facilitate the timely publication of data
To provide advice and support when there are obstacles to progress
To share progress about SIOPEN clinical trials
To develop SOPs for SIOPEN clinical trial conduct

If you have a new study concept or proposal, then please let us know details and we will be pleased to offer our support. Please contact us.

You can find hereunder the list of the SIOPEN clinical trials (to get more details please go to the clinical trial page here):

SIOPEN Low and Intermediate Risk Neuroblastoma European Study (LINES)
VERITAS (Trial Evaluating and Comparing Two Intensification Treatment Strategies for Metastatic Neuroblastoma Patients With a Poor Response to Induction Chemotherapy
A randomised phase IIb trial of BEvACizumab added to Temozolomide ± IrinOtecan for children with refractory/relapsed Neuroblastoma (The BEACON trial)
A Multi-Arm, Multi-Stage Platform Trial For Relapsed Neuroblastoma (BEACON-2)
Spinal cord compression
A Phase I study of 131-1 mIBG followed by Nivolumab and Dinutuximab beta Antibody in children with relapsed/refractory Neuroblastoma. (The MINIVAN trial)
Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma (RIST-rNB-2011)
Prospective multicentre clinical trial for risk estimation and treatment stratification in low and intermediate risk neuroblastoma patients (NB2015-LR)

Interested in joining the Specialty committee?

Please first register to become a SIOPEN member and then contact the specialty committee chair and/or co-chair in order to join the committee.

Bone Marrow